Comprehensive understanding of the kidney, better kidney care

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Kidney is an important organ of human body, which is closely related to life safety. Foragers also pay attention to the maintenance of the kidney in daily lifeBut because of a lack of comprehensive understanding of the kidney and ignore a lot of "kidney injury behavior". Today, Mutual Aid will lead you to understand the kidneys comprehensively, to better love and protect them.


01 Kidney function ≠ reproductive function

Kidney is an important organ in the body, whichCan maintain water balance, pH balance and discharge metabolites. Kidney deficiency is the "introductory" interpretation of kidney impairment, and it is manifested as poor intercourse for men and unfavorable fertility for women. This is actually wrong!


In particular, it is important to emphasize that sexual or reproductive dysfunction cannot be equated with kidney deficiency. Poor intercourse in men is usually the result of some common clinical male diseases, such as prostatitis and prostate enlargement, while infertility in women is usually related to gynecological diseases, such as irregular menstruation, ovulation disorders, organic lesions of the uterus, etc.

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In this context, when we talk about kidney functionWeRefer to the effects of diseases of the kidney itself, which generally refer to kidney diseases due to various causes, including acute and chronic glomerulonephritis, acute and chronic pyelonephritis, acute and chronic renal failure, renal vascular disease, nephrotic syndrome and other kidney lesIons.

As the kidneys are important organs, the normal functioning of the body is closely related to its health, so both sexual function and reproductive reproduction, need strong kidneys as a back-up support.


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02 How to quickly determine the state of the kidneys


As mentioned earlier, the kidneys are the main force in maintaining the water balance and acid-base balance. Then to know whether the balance is broken and to determine whether the kidneys are inflamed, we need to focus on these 3 indicators.


01Blood creatInine

Creatinine in blood is the end product of metabolism excreted by the kidneys. Compared with urea, creatinineAfter filtration from the glomerulus, is not reabsorbed by the renal tubules and is less affected by dietary factors, so blood creatinine and endogenous creatinine clearance can more accurately reflect the glomerular filtration rate, that is, the excretory function of the kidney.


02Urinary protein

Protein is an indispensable presence for life activities, and there is also a quantitative amount of protein in the blood. Part of the protein will be filtered through the kidneys into the urine, but will be absorbed and utilized back into the blood in the renal tubules, so if the kidneys and urinary tubules are abnormal, the protein will leak out and become proteinuria.

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24-hour urine protein is the gold standard for diagnosing pathological proteinuriaAnd is one of the main ways to assist SLE patients in monitoring kidney damage.


03Glomerular Filtration Rate

It is the most important indicator of kidney function in the grand finale. It is the plasma volume filtered from the glomerulus per minute, which is 125 ml/min in normal people.Its different values reflect the different states of the kidneys.

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Comprehensive understanding of the kidney, better kidney care

For example, increased filtration rate can be seen in the early stage of diabetic glomerulosclerosis, some micro lesion type nephrotic syndrome, etc. These abnormalities are related to the morphology of the glomerulus; for example, decreased filtration rate can be seen in various primary and secondary renal diseases as well as the gradual decrease of filtration rate with age.


Based on the characteristics of these indicators we know that key indicators can reflect the degree of kidney damage. The same holds true for lupus nephritis.


According to the literatureGlomerular filtration rate tends to decrease continuously as the disease progresses in lupus nephritis, 24-hour urine protein is abnormal in the early stage of the disease and continues to increase throughout the course of the disease, and blood creatinine is not significantly abnormal in the early stage of lupus nephritis but shows progressive damage as the disease progresses.

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03 How to stay away from "kidney-damaging behaviors


Professor Yu Feng of the Department of Nephrology, Peking University First Hospital, shared in a public service broadcast of the SLE Support Circle that 50% of SLE patients have obvious evidence of kidney involvement in clinical diagnosis, and that kidney involvement can be found in nearly 100% of lupus patients through pathological biopsy by kidney puncture.

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As the main target organ involved in SLE, the degree of damage to the kidney is closely related to the prognosis of lupus patients. In the course of communication with patients, we found that some patients showed obvious indicators of kidney involvement not long after diagnosis, while others had not had any kidney-related abnormalities for many years after diagnosis.

After excluding the individuality of body functions, this situation isAlso related to the good habits of thesePatients.


01Maintain good dietary habIts

It is recommended that foragers can implement aDiet that is low in sodium, moderate in quality protein, adequate in carbohydrates and rich in vitamins. Because a high-sodium diet can lead to edema, while a high-fat and high-sugar diet can increase the accumulation of lipids in the blood vessels, leading to increased blood pressure and aggravated anemia, which in turn affects the normal detoxification of the kidney.


02Do not stay up late

It is said that staying up late hurts the liver, in fact, staying up late also hurtsThe kidneys. The main force of the kidney-glomerulus is a fixed number, they need to work non-stop to discharge metabolites when the brain is awake, only in the sleep state, arrange part of the glomerulus into dormancy, maintaining a lower level of activity.

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If you stay up late for a long time, the glomerulus overworked, it will lead to glomerular overload "sick" or "apoptosis", so that the kidney function will be affected.

03Maintain good lifestyle habits

You must stay away from smoking and alcohol, which can lead to acidification, loss of appetite, headache and dizziness, microvascular constriction and other adverse reactions, making the already uncomfortable kidney burden even heavier. In additionDrinking enough water, not holding urine and not sitting downAre also tips to take care of the kidneys.


04Rational use of medication

SLE patients need to take medication for a long time, and when taking tacrolimus, cyclosporine, methotrexate and other immunosuppressive drugs, they need to monitor their liver and kidney functions regularly. In addition, drugs should not be abused, especially anti-inflammatory and analgesic drugs, and the so-called prescriptions. Improper use of drugs can easily cause serious damage to the kidneys.

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05Keep your emotions calm

In Chinese medicine, there is a saying that "fear hurts the kidneys", which also applies to SLE patients. Fear, depression, anxiety and other negative emotions will directly affect the progression of SLE and may induce lupus nephritis during the progression of SLE.

Therefore, foragers should keep their emotions calm and communicate with their families or talk to their patients in patient groups when they are uncomfortable or tormented.

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In the face of SLE, it is not shameful to escape but useless. Only by facing up to the difficulties and starting from the little things in life, can we build a strong defense against the disease.